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2 New Malaria Treatments Announced as Drug Resistance Grows

Novartis' GanLum showed a 97.4% PCR-corrected cure rate in a Phase 3 trial across 12 African countries, offering a new option against drug-resistant malaria.

  • A single-dose malaria treatment combining four drugs was found to be just as effective as the standard six-dose course over three days that many patients do not complete.
  • There is an urgent need for new malaria treatments as parasites are developing resistance to existing artemisinin-based combination therapies in sub-Saharan Africa.
  • In a separate clinical trial, a new drug called ganaplacidelumefantrine cured 97.4% of participants, outperforming an existing treatment at 94% cure rate.
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2 new malaria treatments announced as drug resistance grows

Researchers are reporting two promising approaches to counteract malaria's growing drug resistance. Switzerland-based Novartis has released results for a new experimental drug called GanLum.

·United States
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Nature broke the news in United Kingdom on Wednesday, November 12, 2025.
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