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Katie Couric marks 25 years since televised colonoscopy with new PSA

Katie Couric parodies Sydney Sweeney's ad to urge Americans 45 and older to get screened for colon cancer, a preventable disease causing the second-highest cancer deaths in the U.S.

  • Katie Couric commemorates 25 years since her groundbreaking on-air colonoscopy by starring in a recent awareness campaign that urges people aged 45 and older to undergo colon cancer screening.
  • Couric’s efforts were deeply influenced by the loss of her husband, Jay Monahan, who passed away from colon cancer at the age of 42 in 1998, as well as by increasing colon cancer diagnoses among younger adults.
  • The PSA, featuring Katie Couric, playfully mocks Sydney Sweeney’s controversial American Eagle jeans commercial to promote colon cancer screening awareness through an initiative launched by the Colorectal Cancer Alliance in partnership with Maximum Effort.
  • Couric emphasizes that many individuals tend to overlook or delay cancer screenings, cautioning that the number of colon cancer cases in people under 50 is projected to double by 2030, and highlights the importance of regular reminders to encourage consistent screening.
  • The campaign aims to increase screenings since fewer than 60% of eligible adults are up to date, which could prevent many colon cancer deaths through early polyp detection and removal.
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TMZ broke the news in Los Angeles, United States on Thursday, September 25, 2025.
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