Building Microbial Communities to Improve Antimicrobial Strategies

Building microbial communities to improve antimicrobial strategies

The lack of novel antimicrobial compounds in the development pipeline cries for innovative approaches regarding their discovery. In this Perspective, we discuss how microbial interactions play a significant role in shifting a pathogen’s response to antibacterial treatment and negatively impact patient outcomes. Furthermore, we argue that interspecies interactions are often overlooked in treatment selection and current drug screening approaches, …

High prevalence of low-concentration antimicrobial residues in commercial fish: A public health concern in Bangladesh - AMR Insights

A study in Bangladesh found that antibiotics used in commercial fish farms raise concerns about antimicrobial resistance (AMR) and environmental contamination. The study used Thin Layer Chromatography to detect antimicrobial residues in four fish species, with the highest prevalence observed for Ciprofloxacin in Tilapia, Oxytetracycline in Pabda, and Chlortetracycline in Tilapia. The highest Hazard Quotient (HQ) was for Enrofloxacin in Climbing …

Two-Part Treatment Developed to Overcome Antimicrobial Resistance

Antimicrobial resistance (AMR) towards medicine has been an ongoing concern for the last several decades. The concept that a microbe can build resistance a

Backed by the UN, governments are breaking down antimicrobial resistance

Jacqueline Alvarez, Chief of the Chemicals and Health Branch at the UN Environment Programme (UNEP), explores the importance of holistic, One Health efforts to mitigate the growing threat of antimicrobial resistance It’s been almost a century since the discovery of penicillin, which kickstarted the production of drugs that fundamentally changed the world. Millenia after our species learnt to defend itself against large predators, it successfully…

Engineering farmland soil ecosystems with phages to fight antimicrobial resistance

Resistance to antimicrobial products like antibiotics poses a bigger threat to global health every day. Antimicrobial resistance is tracked closely in clinical settings, but not so well in nonclinical environments like farmland soil—where the genes controlling it can spread rapidly among microbes...