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Top AMR Insights News

New Compound Infuzide Shows Promise Against Resistant Bacterial Infections
Innovation

New Compound Infuzide Shows Promise Against Resistant Bacterial Infections

80% Center coverage: 5 sources
Antimicrobial resistance directly causes more than 1 million deaths every year and contributes to more than 35 million more, according to the World Health Organization. Staphylococcus aureus and Enterococcus sp., 2 gram-positive pathogens highly likely to develop resistance to known treatments, can cause dangerous hospital-acquired and community-acquired infections.See the Story
Researchers Identify Tuberculosis Drug-Resistance Inhibitor and Map Complete Structure of Key Bacterial Pump
Cats · New Zealand

Researchers Identify Tuberculosis Drug-Resistance Inhibitor and Map Complete Structure of Key Bacterial Pump

100% Center coverage: 2 sources
Ōtākou Whakaihu Waka researchers have been part of two studies in the battle against drug resistant strains of Mycobacterium tuberculosis, the cause of tuberculosis.See the Story
Augmentation of Wastewater-Based Epidemiology with Machine Learning to Support Global Health Surveillance
Coronavirus

Augmentation of Wastewater-Based Epidemiology with Machine Learning to Support Global Health Surveillance

100% Center coverage: 1 sources
Wastewater-based epidemiology (WBE) has proven to be a valuable tool for monitoring the evolution and spread of global health threats, from pathogens to antimicrobial resistances. Throughout the COVID-19 pandemic, multiple wastewater surveillance programmes have advanced statistical and machine learning methods for detecting pathogens from wastewater sequencing data and correlating measured targets with the represented population to infer meanin…See the Story

Building Microbial Communities to Improve Antimicrobial Strategies

100% Center coverage: 1 sources
The lack of novel antimicrobial compounds in the development pipeline cries for innovative approaches regarding their discovery. In this Perspective, we discuss how microbial interactions play a significant role in shifting a pathogen’s response to antibacterial treatment and negatively impact patient outcomes. Furthermore, we argue that interspecies interactions are often overlooked in treatment selection and current drug screening approaches, …HealthSee the Story

Light-Guided 'Bacterial Robot' System Tackles Antibiotic Resistance

100% Center coverage: 1 sources
A technique developed by Politecnico di Milano researchers is enabling scientists to control specific bacterial functions using light-sensitive materials. The Engineering of Bacteria to See Light (EOS) project has pioneered a system that allows bacteria to sense light and convert light energy into electrical signals across their membranes without the need for any genetic modification. This method is being explored as a promising solution to the …Health · MilanSee the Story

The impact of antimicrobial use regulations on antimicrobial resistance among Salmonella isolates from bovine samples submitted to a veterinary diagnostic laboratory in Central New York - AMR Insights

The US Food and Drug Administration (FDA) has imposed restrictions on antimicrobial usage in food-producing animals, including the extra-label use of third-generation cephalosporins. However, the impact of these restrictions on the antimicrobial resistance status of important pathogens like Salmonella remains unclear. A study analyzed veterinary diagnostic laboratory data on 2413 Salmonella isolates from submitted bovine samples and found that t…New York State · New YorkRead Article

Converting pig manure into biochar mitigates the antibiotic resistance of vegetable endophytes - AMR Insights

The study investigates the impact of composted manure on the spread of antibiotic resistance genes (ARGs) in vegetable endophytes. The research found that biochar from composted pig manure significantly decreased the diversity of ARGs and MGEs in vegetable endophytes. The abundance of ARGs, MGEs, and bacteria was lower in roots treated with biochar compared to compost. The study suggests that biochar derived from manure can effectively mitigate …Read Article

Antimicrobial resistance surveillance of gram-negative bacteria among solid organ transplant recipients, a 4-year retrospective study - AMR Insights

This study examines the resistance-susceptibility patterns of gram-negative bacteria in patients undergoing solid organ transplantation at Shiraz Transplant Center. The study retrieved 2075 GNB isolates from patients, with E.coli, Klebsiella, Pseudomonas, Acinetobacter, Enterobacter, Citrobacter, and Stenotrophomonas maltophilia being the most common. The majority of the isolates were liver transplant recipients, with carbapenem-resistant Entero…Shiraz · ShirazRead Article

Global distribution of antimicrobial resistance genes in Escherichia coli isolated from wild animals using genomes available in public databases - AMR Insights

The study analyzed the global distribution of antimicrobial-resistant genes (ARGs) in Escherichia coli (E. coli) isolated from wild animals, revealing 159 unique ARGs. The most frequently detected gene was tetracycline-resistant, with Asia having the highest burden of ARGs per genome. Wild animals, particularly birds, carnivores, and those in aquatic environments, showed higher resistance to antibiotics commonly used in humans and animals. These…Read Article

Standardizing multidrug resistance definitions and visualizations to support surveillance across One Health - AMR Insights

The study explores the use of visualizations for multidrug resistance (MDR) data in the One Health spectrum, focusing on the animal health sector. A scoping review and online survey revealed that bar charts, visual antibiograms, heat maps, and network graphs were the most common visualizations. Survey respondents preferred simplistic visualizations, and resistance to multiple antimicrobial categories was the most common. The study concludes that…Germany · GermanyRead Article

Countries agree to update action plan to reduce deaths from antimicrobial resistance - AMR Insights

The Seventy-eighth World Health Assembly has approved an update to the Global Action Plan (GAP) on antimicrobial resistance (AMR). The update aims to provide a practical framework for the next decade to achieve targets and commitments, including a 10% reduction in global deaths associated with bacterial AMR by 2030. The update will reflect a multisectoral One Health approach, aiming to balance and optimize health of people, animals, and ecosyste…Read Article

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