The Regulation and Differentiation of Regulatory T Cells and Their Dysfunction in Autoimmune Diseases

The regulation and differentiation of regulatory T cells and their dysfunction in autoimmune diseases

The discovery of FOXP3+ regulatory T (Treg) cells as a distinct cell lineage with a central role in regulating immune responses provided a deeper understanding of self-tolerance. The transcription factor FOXP3 serves a key role in Treg cell lineage determination and maintenance, but is not sufficient to enable the full potential of Treg cell suppression, indicating that other factors orchestrate the fine-tuning of Treg cell function. Moreover, F…

This Autoimmune Disease Has Ravaged Women For Centuries. New Treatments Could Finally Change That.

Three new JAK inhibitor medications have hit the market in recent years to treat alopecia. While they don't cure it, they are changing people's lives.