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New Test to Diagnose Coeliac Disease

  • Melbourne researchers developed a new blood test for coeliac disease after the Nexvax2 vaccine trial failed to work.
  • The vaccine trial aimed to treat coeliac disease, but its failure led researchers to focus on diagnosis through immune markers like interleukin 2.
  • The test mixes a blood sample with gluten fragments to detect T cells, diagnosing coeliac disease accurately without requiring patients to eat gluten.
  • A study of 181 samples showed the test has 90 per cent accuracy and differentiates coeliac disease from gluten intolerance, which it excludes.
  • The blood test could reduce invasive gastroscopies and gluten challenges, making diagnosis easier and is expected to be available within two years.
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Celiac disease is more than just abdominal pain – gluten intolerance can have serious consequences. Those affected must consistently renounce gluten.

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scimex.org broke the news in on Monday, June 9, 2025.
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