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Levels of the Nicotine Analog 6-Methyl Nicotine as a Naturally Formed Tobacco Alkaloid in Tobacco and Tobacco Products

Summary by Nature
S-6-methyl nicotine (S-6MN) has appeared as a nicotine substitute in commercial electronic e-cigarette products and pouches, including with the claim that such use is not regulated under current U.S. law. This work describes an analytical chemistry based search for the natural S/R presence of 6MN and three other MN compounds in additive-free cured leaf tobaccos and in multiple commercial tobacco products. The samples were extracted using 5 N NaO…

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La Repubblica broke the news in Turin, Italy on Tuesday, May 27, 2025.
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