US EditionParkinson’s Disease Multimodal Imaging: F-DOPA PET, Neuromelanin-Sensitive and Quantitative Iron-Sensitive MRI
4 Articles
4 Articles
Parkinson’s disease multimodal imaging: F-DOPA PET, neuromelanin-sensitive and quantitative iron-sensitive MRI
Parkinson’s disease (PD) is a neurodegenerative synucleinopathy characterized by the degeneration of neuromelanin (NM)-containing dopaminergic neurons and deposition of iron in the substantia nigra (SN). How regional NM loss and iron accumulation within specific areas of SN relate to nigro-striatal dysfunction needs to be clarified. We measured dopaminergic function in pre- and postcommissural putamen by [18F]DOPA PET in 23 Parkinson’s disease p…
Using biomechanical and cardiac data, Dr. Patricio Arrué's research seeks to detect the disease through a test that could even be integrated as a function of smart watches. More than 10 million people worldwide suffer from Parkinson's disease (PD), a figure that has doubled in the last 25 years according to data from the World Health Organization (WHO). This reality is the one that motivates Dr. Patricio Arrué, academic of the Department of Mech…
The experimental device allows early signs of parkinson to be detected in writing with high accuracy.
Cortical Effects of Dopamine Replacement Account for Clinical Response Variability in Parkinson's Disease - Science in Vancouver
Individual variability in clinical response to dopamine replacement therapy (DRT) is a key barrier to efficacious treatment for patients with Parkinson’s disease (PD). A better understanding of the neurobiological sources of such interindividual differences is necessary to personalize DRT prescribing, inform future clinical interventions, and motivate translational research. Objective One potential source of this variability is an unintended sec…
Coverage Details
Bias Distribution
- 100% of the sources are Center
To view factuality data please Upgrade to Premium
