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Top Science in Vancouver News

Alzheimer's DiseaseA new study from scientists at the Buck Institute for Research on Aging has revealed a surprising player in the battle against Alzheimer's disease and other forms of dementia: brain sugar metabolism.See the Story
Glycogen Metabolism in Neurons Emerges as Key to Fighting Alzheimer's
67% Center coverage: 3 sources

Parkinson's DiseaseMajor depressive disorder (MDD) is a common neuropsychiatric disorder characterized by diverse symptoms. Although several antidepressants can influence dopamine system in the medial prefrontal cortex (mPFC), but the role of D1R or D2R subtypes of dopamine receptor during anti-depression process is still vague in PFC region. To address this question, we investigate the antidepressant effect of levo-stepholidine (l-SPD), an antipsychotic medicatio…See the Story
Activation of D1R/PKA/mTOR Signaling Cascade in Medial Prefrontal Cortex Underlying the Antidepressant Effects of L-SPD
100% Center coverage: 2 sources

Parkinson's DiseaseParkinson’s disease (PD) is a neurodegenerative synucleinopathy characterized by the degeneration of neuromelanin (NM)-containing dopaminergic neurons and deposition of iron in the substantia nigra (SN). How regional NM loss and iron accumulation within specific areas of SN relate to nigro-striatal dysfunction needs to be clarified. We measured dopaminergic function in pre- and postcommissural putamen by [18F]DOPA PET in 23 Parkinson’s disease p…See the Story
Parkinson’s Disease Multimodal Imaging: F-DOPA PET, Neuromelanin-Sensitive and Quantitative Iron-Sensitive MRI
100% Center coverage: 1 sources