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It’s a Girl — Again! And Again! Why a Baby’s Sex Isn’t Random

UNITED STATES, JUL 18 – Families with three children of the same sex have up to a 61% chance of having another child of that sex, influenced by maternal age and specific genetic variants.

  • Friday's publication in Science Advances showed families with three boys have a 61% chance of having another boy, indicating a family-specific probability influenced by genetics and maternal age.
  • Drawing on the Nurse’s Health Study of over 58,000 women from 1956 to 2015, Wang explained that women who have their first child after age 28 are about 10% more likely to have only boys or only girls.
  • A genomic analysis revealed two common variants linked to single-sex sibling sets, namely NSUN6 associated with female-only offspring and TSHZ1 with male-only offspring.
  • Families desiring children of both sexes should note skewed odds, the authors wrote, and Alex Polyakov said `Based on these findings, you have to tell couples that their chance of having a different-sex child from what they already have is actually less than 50:50`.
  • Looking ahead, Jorge Chavarro says, the study is the “first draft of biological explanation,” and researchers noted more research is needed to clarify the factors behind these sex-ratio patterns.
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31 Articles

Lean Right

Actually, boys and girls should be born with the same probability, but in some families only sons are born, in others only daughters. Researchers discover a clear pattern.

·Dortmund, Germany
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Lean Left

According to a study, the age of the mother can also determine the sex of the child.

kreiszeitung.dekreiszeitung.de
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Center

"Should we try again to get another girl after two boys?" For some families, gender is a motivation for additional offspring. A study could sober them up.

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Nature broke the news in United Kingdom on Friday, July 18, 2025.
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