US EditionSide Effects of Low-Dose Tamoxifen: Results From a Six-Armed Randomised Controlled Trial in Healthy Women
4 Articles
4 Articles
Side effects of low-dose tamoxifen: results from a six-armed randomised controlled trial in healthy women
Adherence to adjuvant tamoxifen therapy is suboptimal, and acceptance of tamoxifen for primary prevention is poor. Published results indicate effect of low-dose tamoxifen therapy. Using questionnaire data from a randomised controlled trial, we describe side effects of standard and low-dose tamoxifen in healthy women. In the KARISMA trial, 1440 healthy women were randomised to 6 months of daily intake of 20, 10, 5, 2.5, 1 mg of tamoxifen or place…
Women are almost twice as likely as men to experience an adverse drug reaction. Various therapeutic groups show gender differences, such as those used for cardiovascular and nervous system pathologies, primarily psychopharmaceuticals. Some specific examples are the highest rate of dependence, somnolence, and falls by benzodiazepines in women. Myalgia, newly occurring diabetes, or liver damage by statins are also more common in women. Other more …
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hablandoenplata.esWomen are almost twice as likely to experience adverse drug reactions, a situation that stems from the "classic exclusion" of women in clinical trials and then extrapolate the results obtained in men, regardless of biological differences, as explained by the specialists in Clinical Pharmacology María Isabel Lucena González and Encarnación Blanco Reina.
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