US EditionExamining the Link Between Gut Inflammation and Parkinson’s Disease
- In June 2024, researchers proposed a hypothesis connecting Parkinson’s disease with gut inflammation and imbalances in the microbiota during a major international conference on inflammation held in Rome.
- This hypothesis arose from observations of inflammatory markers in the gut and brain, and correlations between microbiota changes and neurodegeneration.
- A study analyzing 228 spit and stool samples found more harmful bacteria in the guts of patients with mild cognitive impairment and Parkinson's dementia, suggesting toxins may promote inflammation and cognitive decline.
- Experts suggest that toxins produced in the gut and bacteria found in the mouth may serve as indicators to identify Parkinson’s patients who are more likely to develop dementia, with Dr. Giovanni Barbara highlighting increasing support for the bidirectional interaction between the gut and the brain.
- These findings may guide development of gut-targeted anti-inflammatory treatments to potentially slow or manage Parkinson's progression by promoting a healthy microbiome.
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Health experts warn that Polysorbate 80, an emulsifier found in ice cream, may disrupt gut bacteria balance. They say it is linked to conditions like Crohn's disease, colitis and autoimmune flares.
·New York, United States
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Examining the link between gut inflammation and Parkinson’s disease
Recent research outlined at conference in Rome suggests a relationship between neurodegeneration and alterations in the microbiome. Recent research outlined at conference in Rome suggests a relationship between neurodegeneration and alterations in the microbiome.
·United Kingdom
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59-year-old Andrew Cassy is one of the first people in the world to have stem cells – developed by a Danish researcher – injected into his brain. The hope is that it can cure his disease.
·Copenhagen, Denmark
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