This single-dose drug could help lower ‘bad’ cholesterol

Wonder drug ‘cuts cholesterol in half – after just one dose’, scientists say

Scientists say a cutting-edge gene-editing treatment could help people cut harmful high cholesterol levels in half, after just one treatment.

This single-dose drug could help lower ‘bad’ cholesterol

One-off lipid-lowering gene therapy a success in world-first human trial

In a world-first trial, scientists used a one-off CRISPR gene edit to switch off a liver “fat brake” gene, slashing stubborn LDL cholesterol and triglycerides in patients whose levels refused to budge on standard treatments.Continue ReadingCategory: Medical Innovations, Body and MindTags: Heart Disease, Low-density lipoprotein (LDL) cholesterol, Cholesterol, gene therapy, clinical trials, Monash University

A Gene-Editing Therapy Cut Cholesterol Levels by Half

(Wired) – An experimental gene-editing therapy developed by Crispr Therapeutics is showing promise for treating heart disease. In a step toward the wider use of gene editing, a treatment that uses Crispr successfully slashed high cholesterol levels in a small number of people. In a trial conducted by Swiss biotech company Crispr Therapeutics, 15 participants received a one-time infusion meant to switch off a gene in the liver called ANGPTL3. Tho…