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Why the Mid-30s Are a Major Turning Point for Men's Heart Health

Men’s 10-year cardiovascular risk starts rising around age 35 and reaches significant levels 7 years earlier than women, driven mainly by coronary heart disease, study shows.

  • Researchers found men’s cardiovascular risk begins to diverge around age 35, with men facing higher risk than women, as published Wednesday in the journal.
  • Differences in biology and care patterns may explain the gap, as young adult women have more preventive visits while young adult men delay risk detection; sex hormones and cholesterol also partly explain disparities beyond traditional risk factors.
  • Using rolling 10-year risk windows on CARDIA cohort data, men reached a 5 percent cardiovascular incidence at 50.5 years versus 57.5 for women after around 34 years of follow-up with 227 men who experienced cardiovascular events.
  • Experts urged earlier screening for men, as updated risk equations now allow clinicians to estimate risk from age 30, supporting preventive care visits among young men.
  • Most of the sex gap is driven by coronary heart disease, while researchers caution that women’s risk can accelerate after menopause , with heart disease as a leading cause of death.
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Why the mid-30s are a major turning point for men's heart health

Men develop a greater risk of cardiovascular disease years earlier than women — starting at around age 35, according to a new long-term study.

·Portland, United States
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Heart disease is often considered to be a condition of older age. However, a long-term study now shows that in men the risk increases significantly earlier than in women.

In men and women, the risk of cardiovascular disease is comparable up to about 35 years of age – after that, however, it increases significantly faster in men.

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Science Alert broke the news in Australia on Monday, February 2, 2026.
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