'Old' Brains Increase Risk of Death, Alzheimer's, Study Says
SANTA CLARA COUNTY, CALIFORNIA, JUL 9 – The blood test analyzes nearly 3,000 proteins to predict aging speed of 11 organs and risks for diseases like Alzheimer's, with brain age strongly linked to mortality, researchers said.
- In Nature Medicine Wednesday, Stanford University researchers unveiled a blood-based tool, spearheaded by Tony Wyss-Coray, that computes organ biological age from a single blood vial.
- Recognizing chronological age's limits highlighted the need for biological age, processed for 45,000 UK Biobank participants over 17 years.
- Using advanced laboratory technology describes nearly 3,000 proteins in blood samples, an artificial intelligence algorithm compares protein levels to age-adjusted averages.
- Wyss-Coray said, 'Assess the age of an organ today and predict the odds of your getting a disease associated with that organ 10 years later,' highlighting the predictive power of brain's biological age in determining lifespan.
- Despite research-only availability, Wyss-Coray plans to commercialize the tool within two to three years, according to his statement.
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Stanford researchers develop new tool to measure biological age
Researchers at Stanford University have developed a new tool that can compute the “biological age” of human organs by processing a single vial of blood. The tool, unveiled in Nature Medicine Wednesday morning, was developed by a research team spearheaded by Tony Wyss-Coray. Wyss-Coray, a Stanford Medicine professor who has spent almost 15 years fixated on the study of aging, said that the tool could “change our approach to health care.” “It coul…
'Old' brains increase risk of death, Alzheimer's, study says
People with "young" brains -- brains aging more slowly than their actual age -- are much less likely to die or develop Alzheimer's disease than those with "old" brains suffering from accelerated aging, researchers say.
Plasma proteomics links brain and immune system aging with healthspan and longevity
Plasma proteins derived from specific organs can estimate organ age and mortality, but their sensitivity to environmental factors and their robustness in forecasting onset of organ diseases and mortality remain unclear. To address this gap, we estimate the biological age of 11 organs using plasma proteomics data (2,916 proteins) from 44,498 individuals in the UK Biobank. Organ age estimates were sensitive to lifestyle factors and medications and…


Biological age of the brain emerges as a powerful predictor of longevity
The candles on your birthday cake don't tell the whole story. As anyone who ever attended a high-school reunion can tell you, some people age faster than others.
Organs age at their own pace – and two of them, according to research, make surprisingly clear decisions about our health and lifespan.
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