US EditionSelective Inhibition of Stromal Mechanosensing Suppresses Cardiac Fibrosis
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Selective Inhibition of Stromal Mechanosensing Suppresses Cardiac Fibrosis
Scientists demonstrated across multiple scales that inhibition of matrix mechanosensing in persistently activated cardiac fibroblasts potentiates—in concert with soluble regulators of the TGFβ pathway—a robust transcriptomic, morphological, and metabolic shift towards quiescence. [Nature] AbstractPress Release
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