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Top Stemwell Science News News

iconPCR™: Powering the Next Wave of Metagenomics and Microbiome Discovery
Billings, Montana · Billings

iconPCR™: Powering the Next Wave of Metagenomics and Microbiome Discovery

92% Center coverage: 13 sources
How a New Approach to PCR is Transforming Microbial ResearchSee the Story
AbbVie’s $2.1B Acquisition Adds In Vivo Cell Therapy to Its Immunology & Inflammation Pipeline
Cancer

AbbVie’s $2.1B Acquisition Adds In Vivo Cell Therapy to Its Immunology & Inflammation Pipeline

87% Center coverage: 8 sources
AbbVie is acquiring Capstan Therapeutics, a startup with technology that enables in vivo engineering of immune cells. The University of Pennsylvania spinout’s lead program recently began a Phase 1 test as a potential treatment for B cell-mediated autoimmune disorders. The post AbbVie’s $2.1B Acquisition Adds In Vivo Cell Therapy to Its Immunology & Inflammation Pipeline appeared first on MedCity News.See the Story
The Supreme Court upholds free preventive care, but its future now rests in RFK Jr.’s hands
Robert F. Kennedy Jr. · United States

The Supreme Court upholds free preventive care, but its future now rests in RFK Jr.’s hands

100% Center coverage: 4 sources
On June 26, 2025, the U.S. Supreme Court handed down a 6-3 ruling that preserves free preventive care under the Affordable Care Act, a popular benefit that helps approximately 150 million Americans stay healthy. See the Story

Targeting a Key Enzyme Could Reverse Early Parkinson's Effects

100% Center coverage: 3 sources
Putting the brakes on an enzyme might rescue neurons that are dying due to a type of Parkinson's disease that's caused by a single genetic mutation, according to a new Stanford Medicine-led study conducted in mice.Parkinson's Disease · StanfordSee the Story

Breast Cancer, Viruses, and Human Leukocyte Antigen (HLA)

Coverage: 2 sources
Several viruses have been implicated in breast cancer, including human herpes virus 4 (HHV4), human herpes virus 5 (HHV5), human papilloma virus (HPV), human JC polyoma virus (JCV), human endogenous retrovirus group K (HERVK), bovine leukemia virus (BLV) and mouse mammary tumor virus (MMTV). Human leukocyte antigen (HLA) is involved in virus elimination and has been shown to influence breast cancer protection/susceptibility. Here we investigated…Breast CancerSee the Story

Liquid Biopsy in Breast Cancer: Clinical Implications of ctDNA and CTCs in Diagnosis, Treatment, and Monitoring

The authors focus on the clinical applications of circulating tumor cells (CTCs) and circulating tumor DNA (ctDNA) in breast cancer progression, relapse, diagnosis, and treatment response. [Molecular and Cellular Biochemistry] AbstractCancer · PortlandSee the Story

The Vps13-Like Protein BLTP2 Regulates Phosphatidylethanolamine Levels to Maintain Plasma Membrane Fluidity and Breast Cancer Aggressiveness

Scientists found that bridge-like lipid transport proteins (BLTPs) facilitated the growth of a triple-negative breast cancer cell line and sustained its aggressiveness in an in vivo model of metastasis, suggesting that maintenance of plasma membrane fluidity by BLTP2 may be critical for tumorigenesis in humans. [Nature Cell Biology] Full ArticleRead Article

Autophagy-Targeted NBR1-P62/SQSTM1 Complexes Promote Breast Cancer Metastasis by Sequestering ITCH

Investigators showed that autophagy normally suppresses breast cancer metastasis by enabling the clearance of NBR1–p62/SQSTM1 complexes that instruct p63-mediated pro-metastatic basal differentiation programs. [Nature Cell Biology] AbstractRead Article

pH-Triggered Delivery of Pirarubicin-Gemcitabine Duo Using Polymeric Nanoparticles for Synergistic Breast Cancer Therapy

Researchers investigated the development of pirarubicin and gemcitabine co-loaded polymeric nanoparticles for synergistic activity against breast cancer cells. [Nanoscale Horizons] AbstractGraphical AbstractBreast CancerRead Article

Discovery of Diaryl Piperidone-Sulfonamide As a Novel Dual-Target Inhibitor of STAT3/CAIX Inducing Ferroptosis in Triple-Negative Breast Cancer Cells

A series of diaryl piperidone-sulfonamide derivatives were designed as dual inhibitors of STAT3/CAIX and ferroptosis inducers for triple-negative breast cancer [Journal of Medicinal Chemistry] AbstractGraphical AbstractRead Article

Chimeric Diphtheria Toxin-CCL8 Cytotoxic Peptide for Breast Cancer Management

The specificity of a chimeric cytotoxic peptide was confirmed in vitro by testing the cytotoxic activity of breast cancer cells overexpressing CCR5, a major CCL8 receptor, and by a neutralizing anti-CCL8 antibody they developed. [Molecular Oncology] Full ArticleRead Article

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