US EditionStudies on mRNA Show It Could Potentially Be Used to Cure HIV
7 Articles
7 Articles
SARS CoV-2 mRNA vaccination exposes latent HIV to Nef-specific CD8+ T-cells
Efforts to cure HIV have focused on reactivating latent proviruses to enable elimination by CD8+ cytotoxic T-cells. Clinical studies of latency reversing agents (LRA) in antiretroviral therapy (ART)-treated individuals have shown increases in HIV transcription, but without reductions in virologic measures, or evidence that HIV-specific CD8+ T-cells were productively engaged. Here, we show that the SARS-CoV-2 mRNA vaccine BNT162b2 activates the R…
Human Immunodeficiency Virus (HIV) is one of the most difficult viruses to cure because it is often hidden. However, this could change, as a team of researchers have “obliged” the virus to reveal itself, which would help to be closer to a possible cure There are many diseases in the world, but some are much more difficult to cure than others. This is due to many aspects: the lack of medicines or therapies to fight it, because no explanation has …
New pathway for mRNA drug delivery shows shape of things to come
New pathway for mRNA drug delivery shows shape of things to come Scientists have discovered that the internal shape of tiny drug-delivery particles – called lipid nanoparticles – has a big impact on how well our cells absorb them, paving the way to more efficient vaccine and drug delivery.
mRNA Technology Adapted from COVID-19 Vaccines Shows Potential in Targeting Dormant HIV Reservoirs
Scientists have utilized mRNA technology, originally de […] The post mRNA Technology Adapted from COVID-19 Vaccines Shows Potential in Targeting Dormant HIV Reservoirs first appeared on GeneOnline News. The post mRNA Technology Adapted from COVID-19 Vaccines Shows Potential in Targeting Dormant HIV Reservoirs appeared first on GeneOnline News.
By Acácio Moraes (Folhapress) – Australian researchers have developed a new method of encapsulating messenger RNA in nanoparticles that is capable of activating HIV in a latent state – in which it does not signal its location to the body, as if it were hiding from the defense system. The study was published in the scientific journal Nature […]
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