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Novo Nordisk to Buy U.S.-Based Akero for Up to $5.2 Billion for Promising Liver Drug

Novo Nordisk will pay $54 per share upfront plus $6 per share contingent on approval for efruxifermin, targeting treatment of MASH with high unmet medical need.

  • On Thursday, Novo Nordisk said it would buy Akero Therapeutics for up to $5.2 billion to add experimental liver drug efruxifermin in CEO Mike Doustdar's first major acquisition.
  • Strategic fit drives the acquisition, given MASH's link to diabetes and obesity, as over 40% have type 2 diabetes and more than 80% live with obesity.
  • Under the terms, Novo will pay $54 per share in cash, totaling 4.7 billion USD, with Akero shareholders receiving a $6 per share CVR if approved by June 30, 2031.
  • Market response reflected investor views on strategic growth and risks as Akero shares jumped more than 19% while Novo Nordisk shares fell nearly 2%, with a $4 billion hit to the 2025 free cash flow outlook.
  • Efruxifermin's clinical data position it as a potentially differentiated therapy; it is in phase 3 SYNCHRONY programme targeting F2-F3 and F4 patients and may be a `cornerstone therapy`, Mike Doustdar said.
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Globe Newswire broke the news in on Thursday, October 9, 2025.
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