US Edition80-Year-Old ‘Superager’ Brains Operate Like Those of a 50-Year Old. Here’s Why
CHICAGO, USA, AUG 7 – Research identifies genetic factors and fewer tau tangles as key to memory preservation in SuperAgers, with 101 individuals currently studied at Northwestern University.
- A quarter-century analysis by Dr. M. Marsel Mesulam’s team was published Thursday in Alzheimer’s & Dementia, reflecting on SuperAger memory preservation.
- According to the Alzheimer's Association, over 7 million Americans live with Alzheimer’s, projected to reach nearly 13 million by 2050, with two copies of APOE4 increasing risk by 60%.
- In the hippocampus, researchers found SuperAgers have three times fewer tau tangles and fewer activated microglia in white matter, suggesting preserved brain health.
- Tamar Gefen said that targeting amyloid plaques may not address the pathology in SuperAgers, highlighting the need for broader treatment approaches for Alzheimer’s disease.
- Looking ahead, researchers are expanding studies of SuperAger neurons to map biochemical signatures and explore genetic-level prevention as technology advances.
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A longitudinal study by Northwestern University of the United States shows, after 25 years of research, that some older people maintain a memory equivalent to that of 50-year-old individuals, thanks to resistant brains and lifestyles marked by sociability Biology explains why we suddenly become older than 44 and 60 years old Being over 80 years old and preserving a memory like that of a 50-year-old person is not just an anecdotal exception.
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Total News Sources12
Leaning Left3Leaning Right0Center7Last UpdatedBias Distribution70% Center
Bias Distribution
- 70% of the sources are Center
70% Center
L 30%
C 70%
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