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Scientists Create Lab-Grown Blood Cells Using 'Hematoids'
Hematoids replicate early blood formation and produce diverse blood cell types, offering new ways to study leukemia and advance personalized regenerative therapies, researchers said.
- On October 13, 2025, University of Cambridge scientists created three-dimensional embryo-like structures called hematoids that produce blood cells, published in Cell Reports.
- Using self-organizing human stem cells, the model mimics natural development without extra protein cocktails and forms three germ layers within days.
- Under the microscope, researchers observed that by day eight, beating heart cells appeared, and by day thirteen, red patches of blood were visible in the hematoids; said Dr. Jitesh Neupane, `It was an exciting moment when the blood red color appeared in the dish—it was visible even to the naked eye.`
- Researchers say hematoids could help screen drugs and model blood disorders such as leukaemia, while enabling production of long-lasting blood stem cells for personalized therapies using a patient's own cells.
- Cambridge has patented the method through Cambridge Enterprise, and because hematoids derive from reprogrammed adult cells, they enable diverse individual-specific genetic studies with ethics committees' approval.
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