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Lithium Deficiency Linked to Alzheimer's Onset, Orotate Restores Memory in Mice

UNITED STATES, AUG 6 – Harvard researchers found lithium orotate reversed Alzheimer's symptoms in mice, reducing plaques by 70% and restoring memory, suggesting potential for low-dose treatment trials.

  • Lithium deficiency may be linked to Alzheimer’s disease, according to research from Harvard University.
  • The team found that lithium orotate can prevent memory loss in mice and does not bind to amyloid plaques.
  • Experts stress the importance of clinical trials to explore lithium orotate's effects on humans, recognizing the study's findings as significant and novel.
  • The Harvard team successfully restored memory function in mice by reintroducing lithium orotate, a less toxic compound, into their diet.
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Scientists say it may be possible to protect aging brains from Alzheimer's with lithium

Discover groundbreaking research from Harvard Medical School revealing lithium's critical role in brain health, aging and potential Alzheimer's treatments.

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Nature broke the news in United Kingdom on Wednesday, August 6, 2025.
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