Neurons throughout the brain embed robust signatures of their anatomical location into spike trains

Neurons throughout the brain embed robust signatures of their anatomical location into spike trains

Neurons in the brain are known to encode diverse information through their spiking activity, primarily reflecting external stimuli and internal states. However, whether individual neurons also embed information about their own anatomical location within their spike patterns remains largely unexplored. Here, we show that machine learning models can predict a neuron’s anatomical location across multiple brain regions and structures based solely on…