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Air pollution may be raising risk of lung cancer in ‘never-smokers’: Study

UNITED STATES, JUL 2 – The largest genomic study of 871 never-smoking lung cancer patients found a 3.9-fold increase in tobacco-related mutations linked to air pollution and carcinogenic herbal medicines.

  • Air pollution and traditional herbal medicines are linked to lung cancer in non-smokers, according to a study published in Nature.
  • The study analyzed lung tumors from 871 non-smokers across four continents and found more mutations in polluted areas.
  • Researchers noted that air pollution leads to significant genetic mutations, more than those from secondhand smoke exposure.
  • Lung cancer is a leading cause of cancer death in the U.S., with non-smokers representing 10 to 25 percent of cases globally.
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The exposure to contaminated air is closely related to the appearance of DNA mutations associated with pulmonary cancer, shows a new international study. Researchers have analyzed hundreds of patients who have never smoked and identified genetic changes similar to those caused by smoking, but also some new, present exclusively to non-smoking people, reports Science Alert.

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A recent study found that breathing contaminated air produces genetic mutations, which could influence the development of lung cancer

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Nature broke the news in United Kingdom on Wednesday, July 2, 2025.
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