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Eggs fertilized with material from human skin cells for first time

The Oregon research team produced 82 fertilizable eggs from skin cells with about 9% reaching early embryo stage, offering hope for infertility treatments and same-sex couples.

  • Researchers developed a technique named 'mitomeiosis' to possibly create eggs from human skin cells, aiming to understand chromosome pairing and segregation better.
  • While lab-created eggs could potentially aid those struggling with infertility, they are still too immature for fertilization.
  • Significant ethical concerns arise regarding the use of this technology, such as the possibility of creating 'designer babies.'
  • Despite the challenges, Shoukhrat Mitalipov believes this could be a crucial step toward enabling many women to have genetically related children.
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American scientists have created early human embryos for the first time by manipulating DNA taken from human skin cells and then fertilizing them with sperm. The technique could overcome infertility due to age or disease. The method could theoretically allow same-sex couples to have genetically related children. But researchers still have many years of work ahead of them.

Lean Left

Researchers have changed human skin cells in such a way that they could be fertilized with sperm. Older women or same-sex couples could open up completely new possibilities.

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Lean Left

The method can help with infertility and allow same-sex couples to have a child genetically related to them, but it still takes time for it to work well.

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ohsu.edu broke the news in on Tuesday, September 30, 2025.
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