‘Sleeping’ Cancer Cells in the Lungs Can Be Roused by COVID and Flu
JUL 30 – The study links immune responses to flu and Covid-19 with reactivation of dormant breast cancer cells, increasing risk of lung metastases in remission patients, researchers say.
- A team from institutions including Montefiore Einstein and Utrecht University reported in Nature on July 30 that respiratory infections such as COVID-19 can reactivate dormant breast cancer cells in the lungs, potentially leading to new metastatic tumors.
- The research integrated findings from mouse models and analysis of breast cancer patient data collected prior to the availability of COVID-19 vaccines to investigate how viral infections may influence cancer recurrence.
- They found respiratory infections like COVID-19 and flu triggered interleukin-6 release, which activated dormant cancer cells causing rapid metastatic tumor growth within two weeks.
- Patients who tested positive for SARS-CoV-2 had nearly double the cancer-related death risk and a 40 percent higher chance of lung metastases compared to negatives, highlighting a significant link.
- The findings imply that cancer survivors should take precautions to avoid infection while researchers develop treatments targeting IL-6 to reduce metastasis risks from viral reactivation.
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A study shows that viral infections such as Covid or the flu could play a role. However, there is criticism of the study. By V. Simon.[more]]>


Coronavirus and influenza infections may play a role in cancer recurrence in previously recovered patients. The viruses appear to be able to reactivate "dormant" breast cancer cells that have ended up in the lungs, at least in mice, international researchers report in Nature.
Flu and Corona can wake up sleeping cancer cells - this is shown by a recently published US study in mice. Even years after an survived cancer, the tumor cells can wake up again.
Common Viruses May Wake Dormant Breast Cancer Cells, Study Finds
Breast cancer patients who have been in remission for years or even decades may still need to be cautious about respiratory infections. Some common viruses may re-awaken a very small number of dormant breast cancer cells within our lungs, according to emerging research. "Dormant cancer cells are like the embers left in an abandoned campfire, and respiratory viruses are like a strong wind that reignites the flames," argues molecular geneticist Ja…
Respiratory viruses, such as the flu virus or SARs-CoV-2, can trigger latent breast cancer cells that have spread to the lungs, which prepares the ground for...


A study in Nature reveals that viruses such as influenza or SARS-CoV-2 can reactivate sleeping tumor cells and favor the appearance of lung metastases.The results in mouse models are backed up by data from thousands of human patients.Respiratory viruses ‘wake up’ metastatic breast cancer cells in the lungs Breast cancer is the most diagnosed among women and one of its main causes of death is metastases, which often appears years after initial re…
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