US EditionForget aspirin: This drug may be better for heart disease
Clopidogrel lowers the risk of major cardiovascular events by 14% compared to aspirin in coronary artery disease patients, without increasing major bleeding, study shows.
- At the European Society of Cardiology Congress in Madrid, researchers presented a pooled analysis showing clopidogrel reduced major cardiovascular or cerebrovascular events by 14% versus aspirin, published in The Lancet.
- Decades of aspirin use prompted an analysis comparing it with clopidogrel, as aspirin has long been prescribed indefinitely in low doses for secondary prevention in coronary artery disease patients.
- Notably, the researchers reported that clopidogrel did not increase major bleeding risk compared with aspirin, with benefits seen across clinical subgroups including those less responsive to clopidogrel.
- Experts say the findings may prompt guideline updates as clopidogrel's low cost and effectiveness could affect treatment for more than 300 million patients with CAD globally, including 2.3 million patients in the UK.
- Researchers warned that further studies are required, noting researchers emphasised the need for cost-effectiveness analysis and broader population studies before changing treatment standards, and patients with CAD are urged to consult their doctor for individual assessment.
11 Articles
11 Articles
The pros and cons of taking a daily aspirin - and what could work better
A medicine called clopidogrel may take over from aspirin’s widespread use as a blood thinner to stop heart attacks and strokes.But as both aspirin and clopidogrel can trigger excess bleeding and stomach ulcers, the decision to use them needs careful discussion with a doctor, experts have said.Blood thinning is an important plank of preventive healthcare, as heart disease and strokes – which are among the commonest causes of death – are usually c…
Blood-thinning pill 'more effective' than aspirin at preventing heart attacks and strokes, scientists say
Doctors have found a drug better than aspirin for warding off heart attacks and strokes in a discovery that could influence clinical guidelines worldwide. Patients have historically been advised to take aspirin to prevent major cardiovascular events due to its blood-thinning effects.In a new study, however, clopidogrel - also a blood thinner - appeared to be more effective at lowering the risk of cardiac events.The findings, presented at the Eur…
A drug called clopidogrel, which has been on the market for some time, has shown better results in coronary patients and the risk of bleeding is not higher either.
When Aspirin fails: Is Clopidogrel the next best option or just part of dual therapy?
For decades, aspirin has been the go‑to drug for preventing heart attacks and strokes. But recent research is turning that assumption on its head. Aspirin has been overtaken by another well-known medication, which is essentially a blood thinner and may be even more beneficial, according to an exciting new study from the European Society of Cardiology congress that was published in The Lancet. Doctors now believe that clopidogrel, a well-known an…
New study finds clopidogrel outperforms aspirin in preventing heart attacks and strokes; here’s what experts have to say
New research suggests clopidogrel may be more effective than aspirin in preventing heart attacks and strokes for patients with coronary artery disease. Experts explain what this means for treatment, safety, and long-term heart health.
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