Exercise eases iron-mediated cell death to aid Parkinson's...

The increase in average life expectancy is increasing the incidence of Parkinson's disease. While the incidence of the disease worldwide varies according to geographic regions and populations, the incidence rates are increasing especially in Western countries. Parkinson's disease is a health problem that affects millions of people worldwide and is constantly being researched for its treatment. First described as a "trembling palsy" by James Park…

Exercise eases iron-mediated cell death to aid Parkinson's...

Physical exercise eased signs of a type of iron-mediated cell death called ferroptosis in microglia and improved neurological function in mouse models of Parkinson’s disease, a study finds. Microglia are a type of nervous system support cell that’s believed to be important in the neurodegenerative disease. When ferroptosis was reduced, the microglia showed an enhanced ability to engulf and clear alpha-synuclein, the protein that accumulates to t…