Increasing physical activity in middle age may protect against Alzheimer's disease
- As part of a long-term Alzheimer's disease study, Mge Akinci and colleagues monitored neurological changes in 337 participants from Catalonia, Spain.
- The study investigated how changes in physical activity over four years affected brain structure and amyloid beta accumulation, a toxic protein linked to Alzheimer's.
- Participants who increased physical activity, even below recommended levels, showed greater cortical thickness, less brain shrinkage, and reduced amyloid beta in memory-related regions.
- Akinci emphasized that even the smallest levels of physical activity provide health advantages, and the study demonstrated a dose-response relationship, where greater increases in exercise were linked to larger decreases in amyloid beta accumulation.
- These results underscore the value of encouraging increased exercise during midlife as an important public health approach to potentially lower the global risk of Alzheimer's disease.
29 Articles
29 Articles
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