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Nate Sheppard's 3-Yard TD, Duke's 2-Point Conversion Stun Clemson 46-45

Duke secured its first win at Clemson in 45 years with a last-minute touchdown and two-point conversion, ending Clemson's six-game home losing streak to power conference teams.

  • On Nov. 1, 2025, the Duke Blue Devils football team defeated the Clemson Tigers football team 46-45 at Memorial Stadium, Clemson, S.C. in a high-scoring shootout with early Duke touchdowns.
  • After last month's home loss to SMU, Clemson's build-up featured contrasting rushing outputs, with 175 yards versus Duke after a previous 35 against SMU.
  • A late pass interference call on Clemson set up a 3-yard touchdown and two-point conversion by Duke quarterback Darian Mensah with 40 seconds left.
  • The loss leaves Clemson's season in jeopardy as the 3-5 record puts the Clemson Tigers football team at risk of missing a bowl, and Dabo Swinney, Clemson coach, erupted in a sideline tirade captured on TV.
  • Clemson hosts Florida State on Nov. 8 next week in a matchup seen as a chance to 'break the curse' at Memorial Stadium, reflecting the pressure after a snapped 40-game home winning streak.
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Nate Sheppard's 3-yard TD, Duke's 2-point conversion stun Clemson 46-45

Nate Sheppard had a 3-yard touchdown run with 40 seconds left and Duke got the two-point conversion to win at Clemson for the first time since 1980 with a 46-45 victory.

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Greenville Online broke the news in Greenville, United States on Saturday, November 1, 2025.
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