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Bird flu virus could risk pandemic worse than COVID if it mutates, France's Institut Pasteur says

Nearly 1,000 human outbreaks with 48% fatality recorded since 2003, and no existing antibodies against H5 strains raise concerns of severe pandemic risk, Institut Pasteur warns.

  • This month, France's Institut Pasteur warned the bird flu could cause a pandemic worse than COVID if it mutates to transmit between humans, Dr Marie-Anne Rameix-Welti said.
  • Spread among wild birds, poultry and mammals has prompted culling of hundreds of millions of birds, disrupting food supplies and raising prices worldwide.
  • WHO data show nearly 1,000 human outbreaks between 2003 and 2025, mainly in Egypt, Indonesia and Vietnam, with 48% fatal; a first-ever human H5N5 case in Washington state this month resulted in the patient's death last week.
  • WOAH officials caution that the risk of a human pandemic remains very low, but experts and authorities say preparedness and early response are essential.
  • People lack antibodies to H5 strains, and unlike COVID-19, flu viruses can kill healthy individuals including children, raising severity concerns.
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Avian influenza could lead to a pandemic worse than that of VOCID-19 if the virus mutates and becomes transmissible between humans, according to the head of the respiratory infections center of the Institut Pasteur....

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(Seoul = Yonhap News) Reporter Lee Shin-young = If the avian influenza (AI) virus mutates to enable transmission between humans, it could lead to a pandemic more serious than COVID-19...

·Korea, Republic of
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With the multiplication of avian influenza in animals, including mammals, the risk of spread in humans is increasing.

·Paris, France
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El Economista broke the news in on Thursday, November 27, 2025.
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