US EditionAncient gene mutation from Black Sea shields against HIV
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Ancient gene mutation from Black Sea shields against HIV
New Delhi: Most humans on the planet possess what is known as the wild-type CCR5 gene, that produces a receptor used by human immune system cells. This receptor is exploited by HIV. Humans from the Black Sea region carry a mutated version of the gene with 32 missing base pairs, called CCR5-Δ32, that disrupts the receptor, and closes the back door that HIV uses to enter human cells. This gene variant is being investigated for use in HIV therapies…
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