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crossNN Is an Explainable Framework for Cross-Platform DNA Methylation-Based Classification of Tumors

Summary by Nature
DNA methylation-based classification of (brain) tumors has emerged as a powerful and indispensable diagnostic technique. Initial implementations used methylation microarrays for data generation, while most current classifiers rely on a fixed methylation feature space. This makes them incompatible with other platforms, especially different flavors of DNA sequencing. Here, we describe crossNN, a neural network-based machine learning framework that…

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"crossNN" of the Charité provides a precise diagnosis of brain tumors to 99.1 percent.

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zdnet.de broke the news in on Friday, June 6, 2025.
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