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Top rarecancernews.com News

ImCheck’s ICT01 Earns FDA Orphan Drug Designation for AML
FDA · United States

ImCheck’s ICT01 Earns FDA Orphan Drug Designation for AML

ImCheck's ICT01 gains an orphan drug designation from the FDA, offering hope for acute myeloid leukemia (AML) treatment in older patients with limited options.See the Story
IGI, Abbvie team up to advance myeloma treatment ISB 2001
AbbVie · Maryland

IGI, Abbvie team up to advance myeloma treatment ISB 2001

Ichnos Glenmark Innovation (IGI) is partnering with Abbvie to advance the development of ISB 2001, a multiple myeloma treatment candidate that’s now in early clinical testing. Under the agreement, Abbvie will receive exclusive rights to develop, manufacture, and commercialize ISB 2001 in North America, Europe, Japan, and Greater China. In return, IGI will receive an upfront payment of $700 million, with eligibility to receive as much as $1.225 b…Read Article
Experts Weigh In on What FDA's Removal of REMS for CAR T Means for Patients, Pharmacists
Cancer · United States

Experts Weigh In on What FDA's Removal of REMS for CAR T Means for Patients, Pharmacists

Debra Patt, MD, PhD, MBA, and Houston Holmes, MD, discuss the ramifications of the FDA's removal of REMS requirements for approved chimeric antigen receptor (CAR) T-cell (CAR T) therapies.See the Story

Quemliclustat named orphan drug by FDA for pancreatic cancer

Quemliclustat has been granted an orphan drug designation in the U.S. as a potential treatment for pancreatic cancer. The U.S. Food and Drug Administration gives this designation to provide extra incentives for companies that are investing in developing treatments for rare diseases, or disorders that affect 200,000 or fewer people in the U.S. The companies are eligible for perks including tax breaks, fee waivers, and a guarantee of seven years m…Maryland · MarylandRead Article

FDA names MB-101 US orphan drug for certain types of glioma

The U.S. Food and Drug Administration (FDA) has granted orphan drug designation to MB-101, a CAR T-cell therapy being developed by Mustang Bio to treat certain forms of malignant glioma, a class of rare brain cancers. Orphan drug status is given to therapies that are intended to treat, diagnose, or prevent rare diseases, defined in the U.S. as those affecting fewer than 200,000 people. This designation provides incentives to encourage companies …Maryland · MarylandRead Article

What do we do with the taboo topic of caregiver anger?

I have quite a lot of friends who are caregivers like me. Every day and night, they provide care, attention, and company to their patients, who have various illnesses like cancer of the liver or prostate, and even myeloma. I also read quite a lot of columns on medical and health websites. Any column written by a caregiver like me always catches my attention. I’ve noticed that no one wants to talk about how angry we can become when we care for a …Read Article

FDA approval sought of relacorilant for platinum-resistant ovarian...

Corcept Therapeutics has asked the U.S. Food and Drug Administration (FDA) to approve relacorilant, to be used in combination with the standard chemotherapy agent nab-paclitaxel, for treating platinum-resistant ovarian cancer. The application is supported by positive data from the pivotal Phase 3 ROSELLA clinical trial (NCT05257408) and other Phase 2 studies, where relacorilant on top of nab-paclitaxel led to slower disease progression and prolo…United States · United StatesRead Article

The art of distraction: Why sometimes we avoid ‘cancer talk’

There is an unspoken rule that seems to apply to all cancer caregivers. It goes something like this: You should always be serious, present, and “on.” It’s as if one must be alert at all times simply because their loved one is suffering from a disease that is as tiring, exhausting, and frustrating as myeloma. However, I have a confession: Ever since my mother’s myeloma diagnosis, some of the most healing moments we’ve spent together have been tim…Mississippi · MississippiRead Article

SENTI-202 granted FDA orphan drug designation for blood cancers

Senti Biosciences‘ experimental cell therapy SENTI-202 has been granted orphan drug designation by the U.S. Food and Drug Administration (FDA) as a potential therapy for hard-to-treat blood cancers, including acute myeloid leukemia (AML). The FDA gives this designation to experimental treatments for rare disorders to encourage investment in drugs, particularly when it may be harder for companies to recoup their costs and turn a profit. The desig…Maryland · MarylandRead Article

GLIX1 named FDA orphan drug for treatment of malignant glioma

The U.S. Food and Drug Administration (FDA) has granted orphan drug designation to GLIX1, a cancer treatment now in the preclinical stages of development, as a potential therapy for malignant glioma, its developer Hemispherian announced. GLIX1 is designed to kill cancer cells by going after the cells’ DNA. The FDA awards orphan drug status to investigational therapies that have the potential to treat disorders that affect fewer than 200,000 peop…United States · United StatesRead Article

Recognizing the Invisible Labor We Perform as Caregivers

I have 27 browser tabs open on my laptop and 33 on my phone. They range from grocery lists with foods low in sodium to an article about a myeloma diagnosis, a study on the side effects of daratumumab, and application forms for medical insurance claims. Although my mum’s myeloma is “stable,” my mind is on fire. What I am experiencing is the invisible labor of caregiving — the effects of the work I do that no one sees. It involves drawing up to-do…United States · United StatesSee the Story

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