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Top dkfz.de News
HealthcareNew research suggests restoring stellate cells to their healthy and protective state could simultaneously reduce liver scarring and improve liver function.See the Story
Secret boss of the liver: Star-shaped cells that promote fibrosis also regulate liver health
100% Center coverage: 1 sources
HealthResearchers have identified genetic changes in blood stem cells from frequent blood donors that support the production of new, non-cancerous cells. Understanding the differences in the mutations that accumulate in our blood stem cells as we age is important to understand how and why blood cancers develop and hopefully how to intervene before the onset of clinical symptoms.See the Story
Beneficial genetic changes observed in regular blood donors
67% Center coverage: 3 sources
Heidelberg, Germany · HeidelbergGliomas are types of cancers that arise in the brain and are extraordinarily difficult to treat. They are the leading cause of brain tumour-related deaths in both children and adults. Two pioneering scientists are awarded The Brain Prize 2025 for their discoveries that open up an entirely new way of thinking about and understanding these […]
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Discover The Brain Prize 2025 Winners: Pioneering research into brain cancer is awarded the world’s largest brain research prize, The Brain Prize - Federation of European Neuroscience Societies
Heidelberg, Germany · HeidelbergThe organs of the female reproductive tract undergo extensive remodeling during each monthly cycle in preparation for ovulation or pregnancy. The effects of this recurring remodeling on the affected organs, including the ovaries, fallopian tubes, uterus, cervix, and vagina, have not yet been sufficiently researched. Much of the work that has been done so far has been based on purely microscopic examinations or has only looked at individual organ…See the Story
Early Excellence in Science Award for Ivana Winkler - German Cancer Research CenterLogo des Deutschen KrebsforschungszentrumsLogo des Deutschen KrebsforschungszentrumLogo der Deutschen Zentren der GesundheitsforschungLogo des Helmholtzinstituts
Medical · HeidelbergAcid reducing medicines from the group of proton pump inhibitors (PPIs) are best-selling drugs that prevent and alleviate stomach problems. PPIs are activated in the acid-producing cells of the stomach, where they block acid production. Researchers made the surprising discovery that zinc-carrying proteins, which are found in all cells, can also activate PPIs -- without the presence of gastric acid. The result could be a key to understanding the …See the Story
Surprising finding for acid reducing drugs
100% Center coverage: 1 sources
Cancer · HeidelbergThe peripheral nervous system (PNS) orchestrates organ function in health and disease. Most cancers including pancreatic ductal adenocarcinoma (PDAC) are infiltrated by PNS neurons, contributing to the complex tumor microenvironment (TME)1,2. However, neuronal cell bodies reside in various PNS ganglia, far from the tumor mass. Thus, cancer or healthy organ-innervating neurons elude current tissue sequencing datasets. To molecularly characterize …See the Story
Characterization of single neurons reprogrammed by pancreatic cancer
100% Center coverage: 1 sources
Medical · GermanyA guardian molecule ensures that liver cells do not lose their identity. This has been discovered by researchers from the German Cancer Research Center (DKFZ), the Hector Institute für Translational Brain Research (HITBR), and from the European Molecular Biology Laboratory (EMBL).See the Story
Guardian molecule found to prevent cancer cells from changing identity
100% Center coverage: 1 sources
Property · GermanyScientists from the German Cancer Research Center (DKFZ) and ShanghaiTech University have developed an innovative method for growing brain tumors of individual patients in the laboratory that mimic the original structure and the molecular property of the parental tumor as closely as possible.See the Story
Innovative brain tumor model offers hope for personalized cancer treatments
100% Center coverage: 1 sources