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Top dkfz.de News

Breast Cancer · Heidelberg

Physical training has a positive effect on the sexual health of women with metastatic breast cancer - German Cancer Research CenterLogo des Deutschen KrebsforschungszentrumsLogo of the German Cancer Research CenterLogo of the German Centers for Health Res

The treatment of metastatic breast cancer is associated with a variety of adverse effects. However, in contrast to clinical side effects (e.g. neutropenia, nausea or vomiting), for which there are established treatment recommendations, sexual and vaginal problems are often still a taboo subject that is rarely discussed and little research is done on it.In the international, randomized controlled PREFERABLE-EFFECT study, 355 women with metastatic See the Story

New York State · New York

Booster for cellular immunotherapy: Immunologist Michel Sadelain awarded Meyenburg Prize - German Cancer Research CenterLogo des Deutschen KrebsforschungszentrumsLogo of the German Cancer Research CenterLogo of the German Centers for Health ResearchLogo o

In 2017, the US Food and Drug Administration (FDA) granted approval for the first time for a completely new treatment for blood cancer in children who could no longer be treated with chemotherapy: they received immunotherapy with their own genetically modified T cells, so-called CAR-T cells. In most patients, the disease responded very well to the treatment – and in many cases, the therapeutic success was permanent, lasting for many years. There See the Story

Heidelberg, Germany · Heidelberg

Resistance mechanism in chronic lymphocytic leukemia identified - German Cancer Research CenterLogo des Deutschen KrebsforschungszentrumsLogo des Deutschen KrebsforschungszentrumLogo der Deutschen Zentren der GesundheitsforschungLogo des Helmholtzinstitut

The drug ibrutinib is a Bruton's tyrosine kinase (BTK) inhibitor. These agents, which have only been available for about ten years, have significantly improved the treatment options for chronic lymphocytic leukemia: BTK inhibitors have a targeted effect on the malignant B cells in CLL. They slow down their uncontrolled proliferation by blocking the Bruton's tyrosine kinase. This enzyme plays an important role in the maturation and proliferation oSee the Story

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