US EditionStudy Supports Lowering Colon Cancer Screening Age
- A 2025 study published in JAMA examined colorectal cancer screening outcomes for Californians aged 45 to 54 who underwent their first colonoscopy through Kaiser Permanente Northern California.
- The study followed 2021 US Preventive Services Task Force guidelines that lowered screening age from 50 to 45 due to rising colorectal cancer rates in adults under 50.
- The study demonstrated that adults between 45 and 49 years old exhibited colorectal neoplasia detection rates comparable to those aged 50 to 54, reinforcing the advantages of beginning screening at a younger age.
- Among 12,031 adults screened, adenomas were found in 35.4% of 45-49-year-olds, with similar rates of advanced adenomas and cancer detection in both groups.
- These findings endorse current screening guidelines starting at 45 and suggest broader adoption could help detect precancerous polyps and reduce colorectal cancer risk.
23 Articles
23 Articles
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Most expert groups recommend starting testing at age 45. This is what you need to know. During a colonoscopy, doctors can detect and remove polyps that could be precancerous growths. By Lauren F. Friedman Colorectal cancer was previously considered to be a disease of [...]
Colon Cancer Is Being Caught Earlier, Research Confirms—When to Start Getting Screened
The statistics don't lie: Colon cancer has risen sharply among people under age 50. In fact, the American Cancer Society reports that in those under 55, colon cancer death rates have been increasing roughly 1 percent each year since the mid-2000s. "It's currently the deadliest cancer among young men and the second deadliest among young women," adds the Colorectal Cancer Alliance.Several scientific theories explain this shift, the most widely cir…
Colonoscopy screening at age 45 yields neoplasia rates close to older adults: Study supports guideline change
Researchers from Kaiser Permanente Northern California reveal that adults aged 45 to 49 undergoing their first screening colonoscopy have neoplasia detection rates similar to those aged 50 to 54, supporting recent guideline changes to begin colorectal cancer screening earlier.
An expert review of current knowledge on the causes and prevention of colorectal cancer in young adults.
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