Yale scientists may have found how Parkinson's disease spreads through the brain
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2 Articles
Yale scientists may have found how Parkinson's disease spreads through the brain
Yale scientists discovered two neuron surface proteins that appear to help spread the toxic protein linked to Parkinson’s disease. Blocking these proteins in mice dramatically reduced disease progression, offering a potential new target for future therapies.
Researchers at Yale School of Medicine have discovered that two proteins on the surface of motor neurons play a crucial role in the spread of Parkinson's disease in the brain. The research, published in the journal Nature Communications, reveals how these proteins facilitate the entry of a misfolded form of the α-synuclein protein into healthy cells. Discovery of transporter proteins The scientists identified the mGluR4 and NPDC1 proteins as tra…
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