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Xylitol may increase the risk of cardiovascular events

Researchers found the highest xylitol blood levels were linked to 57% more cardiovascular events in one cohort and 18% more in another.

  • A new study presented at the European Society of Cardiology's ESC Congress 2026 links high blood levels of xylitol to an increased risk of major cardiovascular events.
  • Researchers analyzed health data from roughly 17,000 individuals across the Canadian Longitudinal Study on Aging and the European Prospective Investigation into Cancer to assess these cardiovascular risks.
  • Over six years, the CLSA cohort showed a 57% higher cardiovascular risk; the EPIC-Norfolk group demonstrated an 18% increased risk over 30 years.
  • Lead author Doctor Marco Witkowski noted, "Our long-term findings in the general population highlight how little we know about the cardiovascular safety of xylitol," calling for further studies.
  • Commenting on the findings, Professor Dan Atar of the ESC Communication Committee noted that while sweeteners are generally regarded as safe, results suggest a dose-dependent relationship warranting further study.
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Xylitol, an artificial sweetener commonly used in chewing gum and mint candies, has been found to increase the risk of heart attack and stroke. A 30-year study involving over 17,000 people showed that this additive disrupts blood composition and triggers clotting.

·Istanbul, Türkiye
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Center

High levels of artificial sweetener xylitol could lead to an increased risk of cardiovascular events such as heart attack or stroke. This is revealed by a study to be presented at the European Society of Cardiology congress in Munich. (ANSA)

·Rome, Italy
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Medical Xpress broke the news in Douglas, United Kingdom on Wednesday, August 26, 2026.
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