US EditionNewly Identified Group of Nerve Cells in the Brain Regulates Bodyweight
- Researchers led by Lucas Mavromatis analyzed data from over 170,000 obese adults with diabetes in the US between 2013 and 2023 to study GLP-1 drugs' effects on cancer risk.
- The study compared GLP-1 receptor agonists to DPP-4 inhibitors, as obesity is a growing cause of cancer and no drugs have proven to lower this risk, prompting evaluation of GLP-1's potential.
- GLP-1 drug users had a 7% lower risk of developing 14 obesity-related cancers, with significant reductions specifically for colon and rectal cancers, and an 8% lower risk of death from any cause.
- Lead researcher Mavromatis stated, “This trial raises the intriguing hypothesis” that GLP-1 medications might modestly reduce cancer risk, while ASCO President Dr. Robin Zon emphasized defining the clinical role in prevention.
- The findings suggest GLP-1 drugs could offer small protective benefits against certain cancers in obese patients, especially women, but researchers call for more studies to confirm causation and effects in non-diabetic populations.
23 Articles
23 Articles
Newly identified group of nerve cells in the brain regulates bodyweight
Obesity is a global health problem that affects many people. In recent years, very promising anti-obesity drugs have been developed. Despite these successes, there are patients who do not respond to these drugs or suffer from side effects. Therefore, there is still an unmet need for therapies. Researchers have now discovered a small group of nerve cells in the hypothalamus of mouse brains that influence eating behavior and weight gain. This disc…
FINALLY: An Oral Spray to Help Melt the Pounds Away * 100PercentFedUp.com * by Noah
Summer is finally here! The bad news is that for many of us, the New Years resolutions are a distant memory and the reality is that we still have extra weight we would like to drop before we hit the beach or the pool or the lake. The good news is that you can still do something to drop that weight – without the needles! Semaglutide – A clinically-trusted GLP-1 receptor agonist, is now available in a fast-acting oral spray. It helps reduce appeti…
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