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RHONJ’s Dolores Catania Shares Important Warning About Injectable Weight Loss Drugs

ST. LOUIS, MISSOURI, JUL 14 – Study finds 77% of men with obesity or type 2 diabetes reached normal testosterone levels after 18 months on GLP-1 weight loss drugs, supporting reproductive health benefits.

  • Presented this week at ENDO 2025 in San Francisco, researchers found that popular GLP-1 receptor agonists reversed low testosterone in men with obesity or Type 2 diabetes, with levels increasing after 18 months of treatment.
  • Experts note that low testosterone can lower bone density, reduce muscle mass, and decrease libido, experts say, as excess abdominal fat interferes with hormone signals to the testicle.
  • Participants had their testosterone levels measured before and during treatment over 18 months with weight loss medications, revealing improvements correlated with pounds shed.
  • According to Dr. Shellsea Portillo Canales, results show a direct correlation between anti-obesity medications and testosterone levels, indicating these drugs may benefit men’s reproductive health and that low testosterone levels can be reversed, Portillo Canales said.
  • Portillo said men on testosterone therapies should closely monitor their levels after starting weight loss medications, suggesting potential hormonal adjustments long-term.
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Medical Xpress broke the news in on Monday, July 14, 2025.
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