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Vaccination-Induced T Cell Responses Maintain Polyclonality with High Antigen Receptor Avidity

Researchers studied a cohort of 29 healthy individuals who received three mRNA vaccinations against SARS-CoV-2 before a breakthrough infection. They characterized the magnitude, phenotype, and clonal composition of CD8 T cell responses against 16 epitope specificities. [Science Immunology] Abstract
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Stemwell Science News broke the news in on Tuesday, October 7, 2025.
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