Unraveling the mechanism to awaken dormant fast-twitch muscle tissue in humans

Unraveling the mechanism to awaken dormant fast-twitch muscle tissue in humans

Type IIb fast-twitch myofibers, known for their rapid contraction speed, are plentiful in small mammals but have largely diminished in humans. Researchers at the University of Tsukuba have discovered that the overexpression of a protein called the large Maf group transcription factor in human muscle cells can reactivate the dormant "Type IIb fast-twitch muscle program."