US EditionTreg-boosting therapy prevents inhibitors in hem A mouse model
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Treg-boosting therapy prevents inhibitors in hem A mouse model
A therapy designed to promote the growth of regulatory T-cells (Tregs) in the body prevented inhibitor development in a mouse model of hemophilia A that was treated with factor replacement therapy, a study showed. Inhibitors, a type of neutralizing antibody some patients develop that can make replacement therapies less effective, are a major barrier to effective hemophilia treatment. “Our work showcases an innovative and effective approach to pr…
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