Multiple Sclerosis: an Immune Attack on Astrocyte-Mediated Ion and Water Homeostasis

Multiple sclerosis: an immune attack on astrocyte-mediated ion and water homeostasis

Multiple sclerosis (MS) is an inflammatory demyelinating disease of the CNS. The chain of events that results in demyelinating lesions is not understood, although most theories assume a primary immune attack on myelin. However, the glial cell adhesion molecule GlialCAM, which forms part of a protein complex in astrocytic endfeet that is crucial for brain ion and water homeostasis, was recently identified as a target for autoimmunity in patients …

Treatments for cancer and multiple sclerosis accepted for use on NHS

The Scottish Medicines Consortium has published advice on four medicines.

Addressing the challenges of MS: Progress, policy, and pathways forward

MS Australia is a national not-for-profit organisation dedicated to improving the lives of those affected by multiple sclerosis. Its remit includes supporting research for treatments and cures, advocating for policy change, and championing the needs of the MS community Multiple sclerosis (MS) is the most common acquired chronic neurological disease affecting young adults, often diagnosed between the ages of 20 and 40, and, in Australia, affects …