US EditionStudy Finds Roots of Mental and Neurodegenerative Disorders in Fetal Brain Cells
NO LOC, JUL 25 – Researchers found genes linked to autism, bipolar disorder, and Alzheimer's act during early fetal brain development, offering new paths for gene therapy and personalized treatments.
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3 Articles
Study finds roots of mental and neurodegenerative disorders in fetal brain cells
The origin of some neuropsychiatric diseases, such as autism, bipolar disorder, or depression, and certain neurodegenerative diseases, Alzheimer's and Parkinson's, can be found in very early stages of brain formation in the fetus. That is, earlier than previously recognized, according to a study by the Hospital del Mar Research Institute and Yale University, published in Nature Communications.
Could Mental Illness Begin Before You're Born?
A groundbreaking study has revealed that genes linked to mental and neurodegenerative disorders, such as autism, depression, and Parkinson’s, begin influencing brain development during the earliest fetal stages. These genes are already active in neural stem cells—the progenitors that form the brain—long before symptoms arise.
Traditionally, research on brain diseases has focused on the study of adults, which is when they manifest themselves, and, in particular, has focused mainly on understanding how genes that have been associated with these diseases over the last decades through genetic studies affect neuronal function. However, for some time now it has been recognized that, although these pathologies manifest after birth, they may have their origin before, during …
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