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Subversion of mRNA Degradation Pathways by EWSR1::FLI1 Represents a Therapeutic Vulnerability in Ewing Sarcoma

Summary by Stemwell Science News
Scientists reported that independently to its canonical roles in transcription, EWSR1::FLI1 also functions as an mRNA decay factor, reshaping mRNA stability in Ewing sarcoma. [Nature Communications] Full Article
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Stemwell Science NewsStemwell Science News

Subversion of mRNA Degradation Pathways by EWSR1::FLI1 Represents a Therapeutic Vulnerability in Ewing Sarcoma

Scientists reported that independently to its canonical roles in transcription, EWSR1::FLI1 also functions as an mRNA decay factor, reshaping mRNA stability in Ewing sarcoma. [Nature Communications] Full Article

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Stemwell Science News broke the news in on Wednesday, July 23, 2025.
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