Organelle Conversations Drive Ferroptosis

Organelle conversations drive ferroptosis

Ferroptosis begins with phospholipid peroxidation, leading to membrane damage rupture and cell death. Although research has surged, the intracellular site for ferroptosis initiation remains uncertain. A study now identifies endoplasmic reticulum–mitochondria appositions as key hubs for phospholipid peroxides and important determinants of ferroptosis sensitivity.

Study: CBD Shown to Protect Human Cartilage Cells From Ferroptosis, a Key Contributor to Osteoarthritis

The Marijuana Herald - Marijuana news and information A new study published in the Journal of Cellular and Molecular Medicine finds that cannabidiol (CBD) may help protect human cartilage cells from ferroptosis, a specific type of cell death linked to the development of osteoarthritis and other orthopedic diseases. Researchers at Paracelsus Medical University evaluated the effects of CBD on human articular chondrocytes exposed to ferroptosis ind…