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New enzyme target could lead to breakthrough therapies for Lyme disease

  • Researchers have identified an enzyme called BbLDH as a potential target for new therapies against Lyme disease and possibly other tick-borne diseases, according to a study published in mBio.
  • Researchers discovered that an enzyme, BbLDH, is essential for the growth and infectivity of Borrelia burgdorferi, the pathogen causing Lyme disease, enabling potential new treatments for this illness and others, as reported by Chunhao Li.
  • Virginia Commonwealth University researchers found that BbLDH is essential for the growth and infectivity of Borrelia burgdorferi in vitro and in vivo.
  • The Maine CDC reported a record 3,218 Lyme disease cases in 2024, with 291 cases logged so far in 2025, highlighting the need for public awareness about tick bite prevention.
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Portland Press HeraldPortland Press Herald
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Tick activity surges in Maine with arrival of warmer weather

If you spot a tick right now, it's most likely an adult deer tick, which can transmit Lyme disease.

·Portland, United States
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Sci Tech Daily broke the news in on Thursday, March 20, 2025.
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