Prioritizing Parkinson’s disease risk genes in genome-wide association loci

Prioritizing Parkinson’s disease risk genes in genome-wide association loci

Many drug targets in ongoing Parkinson’s disease (PD) clinical trials have strong genetic links. While genome-wide association studies (GWAS) nominate regions associated with disease, pinpointing causal genes is challenging. Our aim was to prioritize additional druggable genes underlying PD GWAS signals. The polygenic priority score (PoPS) integrates genome-wide information from MAGMA gene-level associations and over 57,000 gene-level features. …

Research Shows Lion’s Mane Mushroom Can Combat Dementia and Cognitive Decline

Currently, there are more than 55 million people who suffer from dementia worldwide, and nearly 10 million new cases of dementia are diagnosed each year. Cognitive decline has become such a pervasive issue in modern society; it has become normalized across the political spectrum.

Natural Mushroom Compound Shows Promise in Treating Parkinson’s Symptoms

A pilot study by UCSF reveals unexpected results, with psilocybin therapy leading to significant improvements in mood, cognitive function, and motor symptoms. Psilocybin, a naturally occurring compound found in certain mushrooms, has shown potential in treating depression and anxiety. Researchers at UC San Francisco set out to explore whether psilocybin could also benefit individuals with [...]

Thomas Deichsel and Martina Pilgrimm, the group's two initiators, were able to welcome six new interested parties who were interested in the exchange and support among like-minded people. The atmosphere was warm and welcoming right from the start. The participants had the opportunity to share their experiences, ask questions and encourage each other. "It's...

Can we treat Parkinson’s disease without destroying embryos?

This episode explores a breakthrough in Parkinson’s treatment using lab-grown stem cells, potentially avoiding the ethical issues of embryo use. We also tackle why overtreatment of the elderly is common in medicine and how Christians can make wise end-of-life choices.

New study highlights potential of digital mental health intervention for people with Parkinson's – RamaOnHealthcare

Digital mental health interventions can effectively improve the well-being of people with Parkinson's, according to a new study led by researchers at City St George's, University of London.The research, published in the journal Aging & Mental Health, explored the effectiveness of a guided online Acceptance and Commitment Therapy (ACT) program called "PACT" that was tailored [...]