Targeting Immune Cell Recruitment in Atherosclerosis

Targeting immune cell recruitment in atherosclerosis

Atherosclerosis is the primary underlying cause of myocardial infarction and stroke. Atherosclerotic cardiovascular disease is characterized by a chronic inflammatory reaction in medium-to-large-sized arteries, with its onset and perpetuation driven by leukocytes infiltrating the subendothelial space. Activation of endothelial cells triggered by hyperlipidaemia and lipoprotein retention in the arterial intima initiates the accumulation of pro-in…

Equitable Access to Lupus Treatment Essential for Improving Minority Patient Outcomes: Margrit Wiesendanger, MD, PhD

Margrit Wiesendanger, MD, PhD, highlights how social determinants of health and equitable treatment access are critical to improving lupus outcomes, particularly in minority populations.

Remission, Attaining CV Risk Targets Drops CVD Risk in Lupus

Long-term control of cardiovascular risk factors and sustained clinical remission help to mitigate the higher risk for atherosclerosis progression in patients with lupus.